CLINICAL VALUE

Identifying disease activity through metabolic imaging, beyond structural changes

Tumor metabolism is closely linked to the Warburg effect. MR deuterium metabolic imaging sensitively detects metabolites such as lactate, adding a new dimension for early detection, efficacy assessment and mechanistic research.

Core Mechanism

From glucose uptake to energy generation, directly observing the full process of cellular metabolism

After entering cells, deuterium-labeled glucose participates in aerobic glycolysis and downstream mitochondrial oxidative phosphorylation. ²H-MRSI can detect signals such as ²H-Glucose, ²H-Lactate, ²H-Glutamate and HDO, probing the bias of cellular metabolic pathways and changes in flux.

Application Scenarios

Covering early screening of major diseases, efficacy assessment and drug development

Early detection of major diseases

Helps identify metabolic abnormalities, providing new signals for early screening of major diseases such as cancer.

Fast, precise efficacy assessment

Compares metabolic changes before and after treatment to assess response to drugs or treatment plans.

Mechanism & target research

Quantifies metabolic pathways and flux, providing evidence for drug development and target validation.

Personalized precision care

Combines lesion metabolic status to support finer clinical decisions.

Technology Evolution

Metabolic imaging becomes a frontier of MR

MR has progressed from structural imaging and functional imaging toward metabolic imaging, with the observation scale moving from tissue morphology to metabolic changes at the cellular and molecular level.

Structural imaging

Observes macroscopic changes in tissue structure or morphology.

Functional imaging

Observes functional changes of tissue at the molecular level.

Metabolic imaging

Observes cellular metabolic changes at the molecular level, becoming a standard direction for next-generation MR products.